Chromatography Blog

core-shell-vs-porous
Chromatography

Core-shell phases – highest efficiency for all HPLC instruments In the past years manufacturers of HPLC columns and instruments have made different efforts to develop products with high separation efficiency combined with shorter analysis times and higher sample throughput. Modern core-shell technology also meets this demand for high resolution and

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GC Columns
Chromatography

The separation potential of chiral GC phases In the following, we wish to give some information for the selection of chiral GC phases. For this purpose, we have studied the separation properties of representative test substances from different chemical groups on chiral MN columns. The selectivity of the respective phase

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GC Columns
Chromatography

GC columns for enantiomer separation Enantiomer separation is used for chiral substances which are non-superimposable mirror images of each other. Chromatography with chiral stationary phases allows separation of these enantiomers, which otherwise show identical physical and chemical properties. Chiral GC is the method of choice for the analysis of fragrances,

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Purity_HPLC_colums
Chromatography

Chiral separation with efficient polysaccharide/silica phases The chirality of polysaccharides was first used for paper chromatographic separation of racemic amino acid derivatives by Kotake et. al. [6]. The cellulose structure of the paper functions as selector. Further studies used cellulose or potato starch with its ingredient amylose for thin layer

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Purity_HPLC_colums
Chromatography

Separation based on cyclodextrins, bonded to silica gel Especially for chiral separations under reversed phase conditions, phases based on cyclodextrins covalently bonded to a silica matrix via a spacer, have been successful. Cyclodextrins are cyclic oligosaccharides of glucose units. The cyclic structure of a cyclodextrin ring can be described as

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