Post Archive

December 2016

Chromatography

The beneficial concept of HILIC phases The advantage of HILIC phases is the use of water and volatile buffers. The aqueous systems allow a high solubility of polar compounds and a compatibility with ESI-MS detectors. The betaine structure of zwitterionic HILIC phases, such as the newly developed NUCLEODUR®HILIC, facilitates a

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Chromatography

A Useful Complement to Conventional HPLC Phases The methodology behind the more efficient separation of medium-polar and polar compounds applications on HILIC phases has been more frequently published as of late. The advantages and differences of HILIC from NP, RP and ion exchanger phases are described below. HILIC: What´s that? The term

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